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Symbol
Name
ID

Gata1
GATA binding protein 1
MGI:95661

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgA level	Increased circulating IgE level	Neutropenia	Leukocytosis	Transient myeloproliferative syndrome	Splenomegaly	Hepatitis	Eczematoid dermatitis
Disease(s) Associated with GATA1	Increased circulating IgA level	Increased circulating IgE level	Neutropenia	Leukocytosis	Transient myeloproliferative syndrome	Splenomegaly	Hepatitis	Eczematoid dermatitis
beta thalassemia
thrombocytopenia
transient myeloproliferative syndrome
X-linked dyserythropoietic anemia
X-linked thrombocytopenia with beta-thalassemia

Mouse Phenotypes

enlarged spleen

increased spleen weight

abnormal myelopoiesis

abnormal thrombopoiesis

decreased eosinophil cell number

increased neutrophil cell number

abnormal leukocyte cell number

decreased lymphocyte cell number

increased osteoclast cell number

abnormal mononuclear cell morphology

abnormal spleen morphology

abnormal spleen red pulp morphology

decreased spleen red pulp amount

decreased spleen white pulp amount

increased splenocyte number

pale spleen

decreased circulating interleukin-13 level

decreased circulating interleukin-4 level

autoimmune response

Availability

Mouse Genotype

Gata1^tm2Sho/Gata1^tm2Sho

Gata1^tm6Sho/Gata1^tm6Sho

Gata1^Plt13/Gata1⁺

Gata1^tm1Mym/Gata1⁺

Gata1^tm1Sho/Gata1⁺

Gata1^tm1Mym/Y
Tg(Gata1*V205G)1Mym/0

Gata1^tm2Sho/Y

Gata1^tm6Sho/Y

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23